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P63 Mouse mAb IHC Kit

Product Specifications

Background

P63 is a nuclear protein transcription factor located on chromosome 3q27-29. It is a member of p53 gene family and plays an important role in the growth and development of a variety of epithelial organs. P63 was localized in the basal cells of squamous epithelium and urethral epithelium, myoepithelial cells of breast, sweat gland and salivary gland, basal cells of prostate and basal cells of skin squamous epithelium. P63 is a marker of basal cell carcinoma, squamous cell carcinoma and urinary tract transitional cell carcinoma. It can be used in the study of primary skin tumors, metastatic adenocarcinoma, benign and malignant breast lesions and prostate cancer.

Synonyms

AIS, Amplified in squamous cell carcinoma, B (p51A), B (p51B), Chronic ulceRative stomatitis protein, CUSP, DN p63 alpha 1, DNp63, EEC3, id:ibd3516, KeRatinocyte transcription factor, KeRatinocyte transcription factor KET, KET, LMS, MGC115972, MGC192897, NBP, OFC8, OTTHUMP00000209732, OTTHUMP00000209733, OTTHUMP00000209734, OTTHUMP00000209735, OTTHUMP00000209737, OTTHUMP00000209738, OTTHUMP00000209739, OTTHUMP00000209740, OTTHUMP00000209741, OTTHUMP00000209742, OTTHUMP00000209743, OTTHUMP00000209744, p40, p51, P51/P63, p53-related protein p63, p53CP, p63, P63_HUMAN, p73H, p73L, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73L, Transformation related protein 63, Transformation-related protein 63, Trp53rp1, Trp63, Tumor protein 63, Tumor protein p53-competing protein, Tumor protein p53-like, Tumor protein p63, Tumor protein p63 deltaN isoform delta, Tumor protein p73, Tumor protein p73-like

Gene Name

TP63

Gene ID

8626

Swiss Prot

Q9H3D4

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 600 - 680 of the human p63 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human p63 protein, including ΔNp63 and TAp63.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Nuclear

Protein Name

P63

Available Sizes

Frequently Asked Questions

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