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Neurofilament Mouse mAb IHC Kit

Product Specifications

Background

Neurofilament (NF) is a neuron specific intermediate filament protein. It is a polymer composed of subunits of NF-H, NF-M and NF-L. It exists in neurons, neurites, peripheral nerve fibers, sympathetic ganglion cells and adrenal medulla. It is expressed in ganglioneuroma, paraganglioma, cerebellar or peripheral neuroblastoma, adrenal tumor or peripheral pheochromocytoma. It is helpful to the diagnosis and differential diagnosis of neuroblastoma and pheochromocytoma, and to identify the neurons of Hirschsprung's disease.

Synonyms

150 kDa medium, 160 kDa neurofilament protein, 2 kDa neurofilament protein, 200 kDa neurofilament protein, 68 kDa neurofilament protein, AI847934, CMT1F, CMT2CC, CMT2E, FLJ53642, KIAA0845, light molecular weight neurofilament protein, Micro glutamic acid-rich protein, mKIAA0845, Nef3, NEFH, NEFL, NEFM, Neurofilament 3, Neurofilament heavy polypeptide 200 kDa, Neurofilament heavy polypeptide, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament medium polypeptide 150 kDa, Neurofilament medium polypeptide, Neurofilament protein heavy polypeptide, Neurofilament protein light chain, Neurofilament protein light polypeptide, Neurofilament protein medium polypeptide, neurofilament subunit NF-L, Neurofilament triplet H protein, Neurofilament triplet L protein, Neurofilament triplet M protein, neurofilament-3 (150 kD medium), NF-H, NF-L, NF-M, NF160, NF165, NF200, NF68, NFH, NFL, NFM, NFM_HUMAN, PPP1R110, protein phosphatase 1, regulatory subunit 110

Gene Name

NEFL

Gene ID

4747

Swiss Prot

P07196

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 543 of the human Neurofilament protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Neurofilament protein, especilaly NF-L protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

Neurofilament

Available Sizes

Frequently Asked Questions

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