Neurofilament Mouse mAb IHC Kit
Product Specifications
Background
Neurofilament (NF) is a neuron specific intermediate filament protein. It is a polymer composed of subunits of NF-H, NF-M and NF-L. It exists in neurons, neurites, peripheral nerve fibers, sympathetic ganglion cells and adrenal medulla. It is expressed in ganglioneuroma, paraganglioma, cerebellar or peripheral neuroblastoma, adrenal tumor or peripheral pheochromocytoma. It is helpful to the diagnosis and differential diagnosis of neuroblastoma and pheochromocytoma, and to identify the neurons of Hirschsprung's disease.
Synonyms
150 kDa medium, 160 kDa neurofilament protein, 2 kDa neurofilament protein, 200 kDa neurofilament protein, 68 kDa neurofilament protein, AI847934, CMT1F, CMT2CC, CMT2E, FLJ53642, KIAA0845, light molecular weight neurofilament protein, Micro glutamic acid-rich protein, mKIAA0845, Nef3, NEFH, NEFL, NEFM, Neurofilament 3, Neurofilament heavy polypeptide 200 kDa, Neurofilament heavy polypeptide, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament medium polypeptide 150 kDa, Neurofilament medium polypeptide, Neurofilament protein heavy polypeptide, Neurofilament protein light chain, Neurofilament protein light polypeptide, Neurofilament protein medium polypeptide, neurofilament subunit NF-L, Neurofilament triplet H protein, Neurofilament triplet L protein, Neurofilament triplet M protein, neurofilament-3 (150 kD medium), NF-H, NF-L, NF-M, NF160, NF165, NF200, NF68, NFH, NFL, NFM, NFM_HUMAN, PPP1R110, protein phosphatase 1, regulatory subunit 110
Gene Name
NEFL
Gene ID
4747
Swiss Prot
P07196
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 543 of the human Neurofilament protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Neurofilament protein, especilaly NF-L protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
Neurofilament
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items