MUC16 Mouse mAb IHC Kit
Product Specifications
Background
CA125 is a high molecular weight glycoprotein that plays an important role in forming a protective mucous barrier. It is mainly expressed in endometrium, cervical endometrium, fallopian tube epithelial cells and mesothelial cells. However, it is not expressed in normal non menstrual and pregnant ovarie. CA125 is an important marker of ovarian serous adenocarcinoma. It has reference value for the differential diagnosis of serous cystadenocarcinoma and mucinous cystadenocarcinoma. It is mainly used in the study of ovarian cancer and its metastasis.
Synonyms
CA 125, CA-125, CA125, CA125 ovarian cancer antigen, Cancer antigen 125, FLJ14303, MUC 16, MUC-16, MUC16, MUC16_HUMAN, Mucin 16, Mucin 16 cell surface associated, Mucin-16, Mucin16, Ovarian cancer related tumor marker CA125, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125
Gene Name
MUC16
Gene ID
94025
Swiss Prot
Q8WXI7
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region External domain of the CA - 125 molecule of the human MUC16 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CA-125 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous, Cytoplasmic
Protein Name
MUC16
Available Sizes
Curated Selection
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