MUC1 Mouse mAb IHC Kit
Product Specifications
Background
MUC1 is a type I transmembrane protein with a molecular weight of 450 kDa. One of the characteristics of glandular epithelial tissue is the synthesis and secretion of MUC1. It plays an important role in epithelial renewal and differentiation, maintaining epithelial integrity and carcinogenesis and metastasis. Under normal conditions, it is mainly expressed in a variety of tissues and organs, epithelial cells near the lumen or glandular cavity, showing apical expression and polar distribution. It is also expressed in T cells, B cells and dendritic cells of hematopoietic system. It is mainly used to identify tumors of epithelial origin.
Synonyms
ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15-3, CA15. 3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227, DF3 antigen, EMA, Episialin, Epithelial Membrane Antigen, H23 antigen, H23AG, KL 6, KL-6, KL6, Krebs von den Lungen-6, MAM 6, MAM6, MCD, MCKD, MCKD1, Medullary cystic kidney disease 1 (autosomal dominant), Medullary cystic kidney disease, autosomal dominant, MUC 1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, MUC1_HUMAN, Mucin 1, Mucin 1 cell surface associated, Mucin 1 transmembrane, Mucin 1, cell surface associated, Mucin-1 subunit beta, Peanut reactive urinary mucin, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated epithelial membrane antigen, Tumor associated epithelial mucin, Tumor associated mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Gene Name
MUC1
Gene ID
4582
Swiss Prot
P15941
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 200 of the human MUC1 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human MUC1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
MUC1
Available Sizes
Curated Selection
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