KSP-Cadherin Mouse mAb IHC Kit
Product Specifications
Background
KSP-cadherin, also known as cadherin-16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP-cadherin has a sensitivity of up to 100% in renal chromophobe cell carcinoma and 95% in renal eosinophilic adenoma.
Synonyms
CAD16_HUMAN, Cadherin 16, Cadherin 16 KSP cadherin, Cadherin kidney, Cadherin-16, CDH 16, CDH16, Kidney cadherin, Kidney specific cadherin, Kidney-specific cadherin, Ksp cadherin, Ksp-cadherin, PRO1340, UNQ695
Gene Name
CDH16
Gene ID
1014
Swiss Prot
O75309
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 700 - 829 of the human KSP - Cadherin protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human KSP-Cadherin protein, and has no cross reaction with E-cadherin, N-cadherin, P-cadherin.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
KSP-Cadherin
Available Sizes
Frequently Asked Questions
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