IRF-4/MUM1 Mouse mAb IHC Kit
Product Specifications
Background
MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B-cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B-cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T-cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.
Synonyms
Interferon regulatory factor 4, IRF 4, IRF-4, Irf4, IRF4_HUMAN, LSIRF, Lymphocyte specific interferon regulatory factor, Lymphocyte specific IRF, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, MUM 1, MUM1, NF EM5, NF-EM5, NFEM5, PU. 1 interaction partner, Sfpi1/PU. 1 interaction partner, Transcriptional activator PIP
Gene Name
IRF4
Gene ID
3662
Swiss Prot
Q15306
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 350 - 451 of the human IRF - 4/MUM1 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human MUM1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Nuclear
Protein Name
IRF-4/MUM1
Available Sizes
Frequently Asked Questions
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