IGF-2 Mouse mAb IHC Kit
Product Specifications
Background
Insulin-like growth factor II (IGF-2) is the protein hormones which belongs to the family of insulin-like growth factors that share structural similarity to insulin. It is secreted by the liver and circulates in the blood. In fetal, IGF-2 is a major growth factor that regulating fetoplacental development influenced by placental lactogen. It is also involed in tissue differentiation. In adults, IGF-2 is involved in glucose metabolism in liver, adipose tissue and skeletal muscle. It is an imprinted gene, expressed only from the paternal allele. Loss of imprinting is associated with Beckwith-Wiedemann syndrome.
Synonyms
C11orf43, IGF 2, IGF II, IGF-II, IGF2, IGF2_HUMAN, IGFII, INSIGF, insulin like growth factor 2 (somatomedin A), Insulin like Growth Factor 2, Insulin like growth factor II, Insulin like growth factor II precursor, Insulin like growth factor type 2, pp9974, Preptin, putative insulin like growth factor II associated protein, Somatomedin A, Somatomedin-A
Gene Name
IGF2
Gene ID
3481
Swiss Prot
P01344
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human IGF - 2 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human IGF-2 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
IGF-2
Available Sizes
Curated Selection
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