Her-2 Mouse mAb IHC Kit
Product Specifications
Background
HER2 is a proto-oncogene, and its expressed c-erbB-2 is a transmembrane protein of a tyrosine kinase receptor with a molecular weight of 185kDa. The activation of HER2 gene can directly lead to the malignant transformation of some human cells or increase the malignant potential of cells. It is reported that the amplification of HER2 gene results in some breast, gastrointestinal, ovarian and endometrial cancers. Therefore, HER2 is directly targeted as a target drug for Hessaitin and other tumors.
Synonyms
Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, C erb B2/neu protein, CD340, CD340 antigen, Cerb B2/neu protein, CerbB2, Erb b2 receptor tyrosine kinase 2, ErbB-2 proto-oncogene, ERBB2, ERBB2_HUMAN, HER 2, HER 2/NEU, HER2, Herstatin, Human epidermal growth factor receptor 2, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEU, NEU proto oncogene, Neuro/glioblastoma derived oncogene homolog, Neuroblastoma/glioblastoma derived oncogene homolog, NGL, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, Receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase type cell surface receptor HER2, Tyrosine kinase-type cell surface receptor HER2, V erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog), V erb b2 avian erythroblastic leukemia viral oncogene homolog 2, V erb b2 avian erythroblastic leukemia viral oncoprotein 2, V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Gene Name
ERBB2
Gene ID
2064
Swiss Prot
P04626
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 300 - 400 of the human Her - 2 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Her-2 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
Her-2
Available Sizes
Curated Selection
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