GLUT-1 Mouse mAb IHC Kit
Product Specifications
Background
GLUT1, also known as human erythrocyte glucose transporter, is a member of GLUT family. It is a membrane related erythrocyte glucose transporter. Its main function is to transfer glucose into epithelial cells. It mediates the main glucose transport in mammalian blood-brain barrier, and glucose transport in vascular endothelial cells, adipose tissue and myocardium. At present, it is mainly used for the study of diabetic nephropathy and retinopathy. GLUT1 can be expressed in many normal tissues such as breast, stomach, lung and colon, but the expression is increased in malignant tissues. Colorectal cancer is strongly positive for GLUT1, indicating that the increase of GLUT1 expression is related to the degree of malignancy and invasiveness.
Synonyms
Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity), CSE, DYT17, DYT18, DYT9, EIG12, erythrocyte/brain, Erythrocyte/hepatoma glucose transporter, facilitated glucose transporter member 1, Glucose transporter 1, Glucose transporter type 1, Glucose transporter type 1, erythrocyte/brain, GLUT, GLUT-1, GLUT1, GLUT1DS, GLUTB, GT1, GTG1, Gtg3, GTR1_HUMAN, HepG2 glucose transporter, HTLVR, Human T cell leukemia virus (I and II) receptor, MGC141895, MGC141896, PED, RatGTG1, Receptor for HTLV 1 and HTLV 2, SLC2A1, Solute carrier family 2 (facilitated glucose transporter), member 1, Solute carrier family 2, Solute carrier family 2, facilitated glucose transporter member 1
Gene Name
SLC2A1
Gene ID
6513
Swiss Prot
P11166
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 492 of the human GLUT - 1 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human GLUT-1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
GLUT-1
Available Sizes
Curated Selection
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