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GLUT-1 Mouse mAb IHC Kit

Product Specifications

Background

GLUT1, also known as human erythrocyte glucose transporter, is a member of GLUT family. It is a membrane related erythrocyte glucose transporter. Its main function is to transfer glucose into epithelial cells. It mediates the main glucose transport in mammalian blood-brain barrier, and glucose transport in vascular endothelial cells, adipose tissue and myocardium. At present, it is mainly used for the study of diabetic nephropathy and retinopathy. GLUT1 can be expressed in many normal tissues such as breast, stomach, lung and colon, but the expression is increased in malignant tissues. Colorectal cancer is strongly positive for GLUT1, indicating that the increase of GLUT1 expression is related to the degree of malignancy and invasiveness.

Synonyms

Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity), CSE, DYT17, DYT18, DYT9, EIG12, erythrocyte/brain, Erythrocyte/hepatoma glucose transporter, facilitated glucose transporter member 1, Glucose transporter 1, Glucose transporter type 1, Glucose transporter type 1, erythrocyte/brain, GLUT, GLUT-1, GLUT1, GLUT1DS, GLUTB, GT1, GTG1, Gtg3, GTR1_HUMAN, HepG2 glucose transporter, HTLVR, Human T cell leukemia virus (I and II) receptor, MGC141895, MGC141896, PED, RatGTG1, Receptor for HTLV 1 and HTLV 2, SLC2A1, Solute carrier family 2 (facilitated glucose transporter), member 1, Solute carrier family 2, Solute carrier family 2, facilitated glucose transporter member 1

Gene Name

SLC2A1

Gene ID

6513

Swiss Prot

P11166

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 492 of the human GLUT - 1 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human GLUT-1 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Membranous

Protein Name

GLUT-1

Available Sizes

Curated Selection

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