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Galectin 3 Mouse mAb IHC Kit

Product Specifications

Background

Galectin-3 is a member of the β-galactose binding lectin family with a molecular weight of 30 kDa which is a chimeric structure consisting of a β-galactoside binding protein and a laminin. The main role of Galectin-3 on the cell surface is related to the adhesion between similar cells. It is expressed in a variety of organs and tissues, including neutrophils and vascular endothelial cells, but it is obviously absent in normal hepatocytes. Galectin-3 can downregulate the expression of some cancers and breast cancer associated proteins, and promote tumor metastasis. It can be used as a reference index for the degree of tumor deterioration.

Synonyms

90K, 90K MAC 2 BP, Basement membrane autoantigen p105, BTBD17B, Galectin 3 binding protein, Galectin-3-binding protein, L3 antigen, Lectin galactoside binding soluble 3 binding protein, Lectin galactoside-binding soluble 3-binding protein, LG3BP_HUMAN, LGALS3BP, M2BP, Mac 2 binding protein, Mac 2 BP, Mac-2 BP, Mac-2-binding protein, Mac2 BP, MAC2BP, Serum protein 90K, TANGO10B, Transport and golgi organization 10 homolog B, Tumor associated antigen 90K, Tumor-associated antigen 90K

Gene Name

LGALS3

Gene ID

3958

Swiss Prot

P17931

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 150 - 250 of the human Galectin 3 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Galectin 3 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic, Nuclear

Protein Name

Galectin 3

Available Sizes

Frequently Asked Questions

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