Desmin Mouse mAb IHC Kit
Product Specifications
Background
Desmin is an intermediate silk protein with a molecular weight of 53 kDa, which is widely distributed in smooth muscle cells, skeletal muscle cells, cardiomyocytes and myofibroblasts. It is mainly used for the diagnosis and differential diagnosis of smooth muscle tumors and striated muscle tumors. In rhabdomyosarcoma, pleomorphic rhabdomyosarcoma was strongly positive, while embryonic / acinar rhabdomyosarcoma was low or even negative. Myofibroblastoma was positive, and the fibroproliferative small round cell tumor showed paranuclear punctate staining.
Synonyms
CMD1I, CSM1, CSM2, DES, DESM_HUMAN, Desmin, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865
Gene Name
DES
Gene ID
1674
Swiss Prot
P17661
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 470 of the human Desmin protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Desmin protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
Desmin
Available Sizes
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