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Desmin Mouse mAb IHC Kit

Product Specifications

Background

Desmin is an intermediate silk protein with a molecular weight of 53 kDa, which is widely distributed in smooth muscle cells, skeletal muscle cells, cardiomyocytes and myofibroblasts. It is mainly used for the diagnosis and differential diagnosis of smooth muscle tumors and striated muscle tumors. In rhabdomyosarcoma, pleomorphic rhabdomyosarcoma was strongly positive, while embryonic / acinar rhabdomyosarcoma was low or even negative. Myofibroblastoma was positive, and the fibroproliferative small round cell tumor showed paranuclear punctate staining.

Synonyms

CMD1I, CSM1, CSM2, DES, DESM_HUMAN, Desmin, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865

Gene Name

DES

Gene ID

1674

Swiss Prot

P17661

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 470 of the human Desmin protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Desmin protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

Desmin

Available Sizes

Frequently Asked Questions

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