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Cytokeratin 7 Mouse mAb IHC Kit

Product Specifications

Background

CK7 is a cytokeratin with a molecular weight of 54 kDa, which mainly marks glandular epithelium and transitional epithelium. It was positive in the epithelium of breast, thyroid, ovary, endometrium and lung, but negative in the epithelium of gastrointestinal tract, colon and prostate. It is mainly used for the study of epithelial tumors. It is often used in combination with CK20 for differential diagnosis of gastrointestinal adenocarcinoma, lung adenocarcinoma and breast cancer, and combined with EMA for diagnosis of synovial sarcoma.

Synonyms

CK 7, CK-7, CK7, Cytokeratin 7, CytokeRatin-7, D15Wsu77e, K2C7, K2C7_HUMAN, K7, KeRatin 7, KeRatin 7, type II, KeRatin type II cytoskeletal 7, KeRatin, 55K type II cytoskeletal, KeRatin, simple epithelial, KeRatin, simple epithelial type I, K7, KeRatin, type II cytoskeletal 7, KeRatin-7, Krt2-7, KRT7, MGC11625, MGC129731, MGC3625, Sarcolectin, SCL, Type II mesothelial keRatin K7, Type-II keRatin Kb7

Gene Name

KRT7

Gene ID

3855

Swiss Prot

P08729

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 350 - 469 of the human Cytokeratin 7 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic, Membranous

Protein Name

Cytokeratin 7

Available Sizes

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