Cytokeratin 5/6 Mouse mAb IHC Kit
Product Specifications
Background
Cytokeratin 5/6 are high molecular weight keratins, which are normally expressed in squamous epithelium, basal cells of ductal epithelium, mesothelial cells, myoepithelium and basal cells of prostate, but not in glandular epithelium. Most adenocarcinoma are negative, and some adenocarcinoma can be weakly positive. The antibody is mainly used for the differential diagnosis of mesothelioma and adenocarcinoma, as well as the study of benign and malignant tumors of epithelial origin.
Synonyms
58 kDa cytokeratin, CK-5, CK5, Cytokeratin-5, Cytokeratin5, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K2C5_HUMAN, K5, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), Keratin 5, Keratin, keratin complex 2, basic, gene 5, keratin, type II cytoskeletal 5, Keratin-5, Keratin5, KRT 5, Krt5, KRT5A, type II cytoskeletal 5, Type-II keratin Kb5, CK 6A, CK 6B, CK 6C, CK 6D, CK 6E, CK-6B, CK-6C, CK-6E, Cytokeratin 6a, Cytokeratin 6B, Cytokeratin 6C, Cytokeratin 6D, Cytokeratin 6E, Cytokeratin-6B, Cytokeratin-6C, Cytokeratin-6E, K2C6C_HUMAN, K6a keratin, K6b keratin, K6C, K6c keratin, K6d keratin, K6e keratin, Keratin, Keratin K6Human, Rat, Mouse, type II cytoskeletal 6A, Keratin type II cytoskeletal 6B, Keratin type II cytoskeletal 6C, Keratin type II cytoskeletal 6D, Keratin type II cytoskeletal 6E, Keratin-6C, KRT6A, KRT6B, KRT6C, KRT6D, KRT6E, type II cytoskeletal 6C, Type-II keratin Kb12, 58 kDa Cytokeratin antibody, CK-5 antibody, CK5 antibody, Cytokeratin-5 antibody, Cytokeratin5 antibody, DDD antibody, DDD1 antibody, EBS2 antibody, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody, K2C5_HUMAN antibody, K5 antibody, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) antibody, Keratin 5 antibody, Keratin antibody, keratin complex 2, basic, gene 5 antibody, keratin, type II cytoskeletal 5 antibody, Keratin-5 antibody, Keratin5 antibody, KRT 5 antibody, Krt5 antibody, KRT5A antibody, type II cytoskeletal 5 antibody, Type-II keratin Kb5 antibody
Gene Name
KRT5 KRT6A KRT6B KRT6C
Gene ID
3852
Swiss Prot
P13647; P02538; P04259; P48668
Reactivity
Human
Immunogen
Synthetic peptides corresponding to the C - terminal amino acids of human Cytokeratin 5 and the N - terminal amino acids of the human Cytokeratin 6 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can recognize both human CK5 and CK6 protein, and shows no cross reaction with other typies of cytokeratin.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
Cytokeratin 5/6
Available Sizes
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