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Cytokeratin 5 Mouse mAb IHC Kit

Product Specifications

Background

CK5 is a cytokeratin with a molecular weight of 58 kDa. In normal tissues, CK5 is expressed in squamous epithelium, germinal layer cells of some squamous epithelium, basal cells of ductal epithelium, myoepithelial cells and mesothelial cells, and almost no expression in most glandular epithelial cells. Therefore, it can be used for the differential diagnosis of squamous cell carcinoma and adenocarcinoma, mesothelioma and adenocarcinoma, as well as benign and malignant tumors of prostate, breast and salivary gland epithelium.

Synonyms

58 kDa cytokeRatin, CK-5, CK5, CytokeRatin-5, CytokeRatin5, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K2C5_HUMAN, K5, keRatin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), KeRatin 5, KeRatin, keRatin complex 2, basic, gene 5, keRatin, type II cytoskeletal 5, KeRatin-5, KeRatin5, KRT 5, Krt5, KRT5A, type II cytoskeletal 5, Type-II keRatin Kb5

Gene Name

KRT5

Gene ID

3852

Swiss Prot

P13647

Reactivity

Human; Dog

Immunogen

A synthetic peptide corresponding to the amino acid region 500 - 590 of the human Cytokeratin 5 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CK5 protein, and shows no cross reaction with CK6.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic, Membranous

Protein Name

Cytokeratin 5

Available Sizes

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