Cytokeratin 19 Mouse mAb IHC Kit
Product Specifications
Background
CK19 is a cytokeratin with a molecular weight of 40kDa. It is mainly expressed in monolayer epithelium and ductal epithelium, and can be detected in the basal layer of squamous epithelium and epidermis. It is a good marker of epithelial differentiation. It is mainly used for the diagnosis of adenocarcinoma. Hepatocytes do not express CK19, but bile duct epithelium does, so it can be used to distinguish hepatocellular carcinoma from intrahepatic cholangiocarcinoma and metastatic adenocarcinoma. CK19 is partially or weakly expressed in normal thyroid tissue, follicular adenoma, nodular goiter and papillary hyperplasia, but it can be diffusely and strongly expressed in thyroid papillary carcinoma.
Synonyms
KRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19
Gene Name
KRT19
Gene ID
3880
Swiss Prot
P08727
Reactivity
Human
Immunogen
Recombinant protein of the human Cytokeratin 19 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Cytokeratin 19 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
Cytokeratin 19
Available Sizes
Frequently Asked Questions
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