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Cytokeratin 18 Mouse mAb IHC Kit

Product Specifications

Background

CK18 is a cytokeratin with a molecular weight of 45 kDa. It is mainly expressed in monolayer and pseudostratified epithelium, but negative in stratified squamous epithelium. It is expressed in glandular epithelium, transitional epithelium and hepatocytes. It is mainly used for the diagnosis of adenocarcinoma.

Synonyms

CK 18, CK-18, CK18, CYK18, Cytokeratin 18, Cytokeratin endo B, CytokeRatin-18, K 18, K18, K1C18_HUMAN, KA18, KeRatin 18, KeRatin 18, type I, KeRatin D, keRatin, type I cytoskeletal 18, KeRatin-18, Krt18

Gene Name

KRT18

Gene ID

3875

Swiss Prot

P05783

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 200 - 300 of the human Cytokeratin 18 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CK18 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 10, 13, 14, 15, 19, 20.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic, Membranous

Protein Name

Cytokeratin 18

Available Sizes

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