Cytokeratin 17 Mouse mAb IHC Kit
Product Specifications
Background
CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.
Synonyms
39. 1, CK 17, CK-17, CytokeRatin-17, K17, K1C17_HUMAN, KeRatin 17, keRatin 17 epitope S1, keRatin 17 epitope S2, keRatin 17 epitope S4, KeRatin 17, type I, KeRatin, KeRatin type I cytoskeletal 17, keRatin, type i cytoskeletal 17 [version 1], KeRatin-17, KRT17, PC, PC2, PCHC1, type I cytoskeletal 17
Gene Name
KRT17
Gene ID
3872
Swiss Prot
Q04695
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 300 - 432 of the human Cytokeratin 17 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CK17 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
Cytokeratin 17
Available Sizes
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