Cytokeratin 10 Mouse mAb IHC Kit
Product Specifications
Background
CK10 is a type I cytokeratin with a molecular weight of 56. 5kd, which is expressed in cells above the basal layer of stratified epithelium and keratinized epithelium. It plays a role in establishing epidermal barrier of plantar skin. The expression of CK10 is directly proportional to the degree of cell differentiation. Highly differentiated patients are often positive, which is mainly used for the diagnosis of squamous cell carcinoma
Synonyms
BCIE, BIE, CK 10, CK-10, CytokeRatin-10, EHK, K10, K1C10_HUMAN, KeRatin 10, KeRatin 10 type I, KeRatin, KeRatin type i cytoskeletal 10, KeRatin type I cytoskeletal 59 kDa, KeRatin-10, KeRatin10, KPP, KRT10, type I cytoskeletal 10
Gene Name
KRT10
Gene ID
3858
Swiss Prot
P13645
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 500 - 584 of the human Cytokeratin 10 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CK10 protein, and shows no cross reaction with CK4, 5, 6, 7, 8, 14, 15, 18, 19.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
Cytokeratin 10
Available Sizes
Frequently Asked Questions
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