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COX-2 Mouse mAb IHC Kit

Product Specifications

Background

COX has two isomeric forms of COX-1 and COX-2. It is a membrane-bound protease involved in the conversion of arachidonic acid to prostaglandins. COX-2 is an inducible enzyme that participates in the expression of cell growth factors, tumor promoting factors and cytokines, and is highly expressed in breast, lung, and colon cancers. It is mainly used in tumor research and is one of the targets of tumor therapy.

Synonyms

COX 2, COX-2, COX2, Cyclooxygenase 2, Cyclooxygenase 2b, Cyclooxygenase, Cyclooxygenase-2, Cyclooxygenase2, EC 1. 14. 99. 1, fj02a10, Glucocorticoid-regulated inflammatory cyclooxygenase, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase, GRIPGHS, hCox 2, Macrophage activation-associated marker protein P71/73, OTTHUMP00000033524, PES-2, PGG/HS, PGH synthase 2, PGH2_HUMAN, PGHS 2, PGHS-2, PGHS2, PHS 2, PHS II, PHS2, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin endoperoxide synthase 2, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 2 precursor, Prostaglandin G/H synthase and cyclooxygenase, Prostaglandin G/H synthase, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin-endoperoxide synthase 2, PTGS2, ptgs2a, TIS10, TIS10 protein, unp1239, wu:fj02a10

Gene Name

PTGS2

Gene ID

5743

Swiss Prot

P35354

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 500 - 604 of the human COX - 2 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human COX-2 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

COX-2

Available Sizes

Frequently Asked Questions

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