CD8 a Mouse mAb IHC Kit
Product Specifications
Background
CD8 is a 68kDa transmembrane glycoprotein consists of two subunits, αβ heterodimer or αα homodimer linked by a disulfide. CD8 is mainly expressed on the surface of suppress/cytotoxic T cells and NK cells. It is detected to be positive in T-cell large granular lymphocytic leukemia and subcutaneous panniculitis like T-cell lymphoma, and can be a marker for Precursor T lymphoblastic leukemia / lymphoma. CD8 is negative in Mycosis Fungoides and non-hematolymphoid neoplasms.
Synonyms
Alpha polypeptide (p32), CD_antigen=CD8a, CD8, CD8 antigen alpha polypeptide, CD8 antigen alpha polypeptide (p32), CD8 antigen, alpha polypeptide (p32), CD8a, CD8A antigen, CD8A molecule, CD8A_HUMAN, Leu2, Leu2 T lymphocyte antigen, Ly 2, Ly 35, Ly B, Ly2, Ly3, Ly35, LyB, Lyt 2. 1 lymphocyte differentiation antigen (AA at 100), LYT3, MAL, OKT8 T cell antigen, OTTHUMP00000160760, OTTHUMP00000160764, OTTHUMP00000203528, OTTHUMP00000203721, p32, T cell antigen Leu2, T cell co receptor, T lymphocyte differentiation antigen T8/Leu 2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt 2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T cell antigen, T8/Leu-2 T-lymphocyte differentiation antigen
Gene Name
CD8A
Gene ID
925
Swiss Prot
P01732
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 235 of the human CD8 a protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CD8 protein, including two typies of dimer: αβ heterodimer or αα homodimer.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
CD8 a
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
