CD44 Mouse mAb IHC Kit
Product Specifications
Background
CD44 is a cell surface receptor, which belongs to the family of cell adhesion molecules that mediate cell-to-cell and cell-to-matrix adhesion, and interacts with cytoskeletal proteins. CD44 is widely expressed in hematopoietic cells and mesodermal cells and is a marker of these cells. Studies have shown that the loss of CD44 expression is related to invasion, metastasis and progression of lung cancer, prostate cancer, breast cancer, ovarian cancer and malignant melanoma.
Synonyms
CD44 antigen (CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD antigen CD44)
Gene Name
CD44 LHR MDU2 MDU3 MIC4
Gene ID
960
Swiss Prot
P16070
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 200 of the human CD44 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CD44 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
CD44
Available Sizes
Curated Selection
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