CA IX Mouse mAb IHC Kit
Product Specifications
Background
CA IX (Carbonic Anhydrase IX) is a transmembrane protein belonging to the carbonic anhydrase family. It catalyzes the conversion of carbon dioxide and water into bicarbonate and protons in the extracellular environment. CA IX is minimally expressed in normal tissues, primarily found in gastrointestinal epithelial cells, but is highly expressed in various malignant tumors, such as clear cell renal carcinoma, breast cancer, and pancreatic cancer. Its expression is significantly upregulated under hypoxic conditions. Therefore, CA IX has been widely studied as a tumor biomarker and a potential therapeutic target.
Synonyms
G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, CAIX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, RCC-associated antigen G250, pMW1
Gene Name
CA9
Gene ID
768
Swiss Prot
Q16790
Reactivity
Human
Immunogen
Recombinant protein of the human CA IX protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CA IX protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
CA IX
Available Sizes
Curated Selection
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