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Adrenocorticotropin (ACTH) Mouse mAb IHC Kit

Product Specifications

Background

ACTH is a polypeptide hormone secreted by anterior pituitary cells. ACTH effects adrenal gland to product of cortisol and it also mediates bone formation and osteoblast survival. ACTH antibody is mainly used for functional classification of pituitary tumors and differential diagnosis of primary and metastatic pituitary tumors. Studies have shown that abnormal ACTH products are often related to lung small cell carcinoma, so it can be used to detect the distribution of hormone cells in some neuroendocrine tumors, such as pheochromocytoma and carcinoid.

Synonyms

ACTH, Adrenocorticotropic hormone, Adrenocorticotropin, alpha melanocyte stimulating hormone, Alpha MSH, Alpha-MSH, beta endorphin, Beta LPH, beta melanocyte stimulating hormone, Beta MSH, Beta-LPH, Beta-MSH, CLIP, Gamma MSH, Gamma-LPH, Gamma-MSH, Lipotropin beta, Lipotropin gamma, LPH, Melanotropin alpha, Melanotropin, Melanotropin beta, Melanotropin gamma, met enkephalin, MSH, NPP, POC, POMC, pro ACTH endorphin, Proopiomelanocortin, Proopiomelanocortin preproprotein

Gene Name

POMC

Gene ID

5443

Swiss Prot

P01189

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Adrenocorticotropin protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human ACTH protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

Adrenocorticotropin

Available Sizes

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