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Claudin 18.1 (AB1694) Mouse mAb (Ready to Use)

Product Specifications

Background

Claudin 18 is a 27kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.

Synonyms

Claudin 18 antibody, Claudin-18 antibody, CLD18_HUMAN antibody, CLDN18 antibody, SFTA5 antibody, SFTPJ antibody

Gene Name

CLDN18 UNQ778/PRO1572

Gene ID

51208

Swiss Prot

P56856

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Claudin 18. 1 protein.

Clonality

Monoclonal

Source

Monoclonal, Mouse, IgG

Applications

Immunohistochemistry (IHC)

Purification

The antibody was purified by protein G affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can specifically recognize human Claudin 18. 1, while it does not react with the Claudin 18. 2 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Protein Name

Claudin 18. 1

Available Sizes

Frequently Asked Questions

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