Cytokeratin 14 (AB2339) Mouse mAb (Ready to Use)

Product Specifications

Background

CK14 is a member of the Type I family of cytokeratins with a molecular weight of 50kDa, which is expressed in the basal cells of myoepithelium and keratinized squamous epithelium. It is mainly used for the difference between stratified squamous epithelium and monolayer epithelium and the diagnosis of squamous cell carcinoma. Eosinophilic tumors at multiple anatomical sites express CK14, which can be used to distinguish from adenocarcinoma, invasive ductal carcinoma of salivary gland and intraductal carcinoma.

Synonyms

CK 14, CK-14, ck14, Cytokeratin 14, CytokeRatin-14, CytokeRatin14, Dowling Meara, EBS3, EBS4, Epidermolysis bullosa simplex, K14, K1C14_HUMAN, KeRatin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner), KeRatin 14, KeRatin, KeRatin type I cytoskeletal 14, KeRatin, type I cytoskeletal 14, KeRatin-14, KeRatin14, Koebner, Krt 14, Krt14, NFJ, OTTHUMP00000164624, type I cytoskeletal 14

Gene Name

KRT14

Gene ID

3861

Swiss Prot

P02533

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 472 of the human Cytokeratin 14 protein.

Clonality

Monoclonal

Source

Monoclonal, Mouse, IgG

Applications

Immunohistochemistry (IHC)

Purification

The antibody was purified by protein G affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can specifically recognize human CK14 protein. In immunohistochemistry on formalin- fixed, paraffin- embedded tissue sections, the antibody specifically labels the basal cell of squamous epithelial cells and glandular epithelia, myoepithelium and mesothelial cells.