TIMP1 (AB1600) Mouse mAb (Ready to Use)
Product Specifications
Background
TIMP- 1 is a 28 kDa glycoprotein that functions as an inhibitor of matrix metalloproteinases (MMPs), which are key enzymes responsible for degrading major structural proteins of the extracellular matrix (ECM) . Both MMPs and TIMPs play crucial roles in ECM degradation and are involved in tumor invasion and metastasis, serving as major regulatory proteins of malignant tumor progression. TIMP- 1 is upregulated in various cancers, including liver cancer, breast cancer, and colorectal cancer, and can serve as a potential biomarker for tumor progression and prognosis.
Synonyms
Metalloproteinase inhibitor 1, Erythroid-potentiating activity (EPA), Fibroblast collagenase inhibitor (Collagenase inhibitor), Tissue inhibitor of metalloproteinases 1 (TIMP-1), TIMP1, CLGI, TIMP
Gene Name
TIMP1
Gene ID
7076
Swiss Prot
P01033
Host
Mouse
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 50 - 150 of the human TIMP1 protein.
Clonality
Monoclonal
Source
Monoclonal, Mouse, IgG
Applications
Immunohistochemistry (IHC)
Purification
The antibody was purified by protein G affinity chromatography.
Dilution
It has been optimized for direct use, requiring no further dilution.
Modification
Unmodified
Storage Conditions
Store at 4°C. Avoid freeze.
Specificity
The antibody can specifically recognize human TIMP1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Protein Name
TIMP1
Available Sizes
Curated Selection
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