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TGF β Receptor I (AB1598) Mouse mAb (Ready to Use)

Product Specifications

Background

Members of the transforming growth factor β (TGF-β) superfamily are key regulators of cell proliferation, differentiation, development, morphogenesis, and disease pathogenesis. TGF-β signals through three cell surface receptors: type I (RI), type II (RII), and type III (RIII) . Type I and type II receptors are serine/threonine kinases that form heteromeric complexes. Upon ligand binding, type II receptors form a stable complex with type I receptors, leading to phosphorylation and activation of the type I receptor kinase.

Synonyms

AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I; TGF beta Receptor I (TGFBR1)

Gene Name

TGFBR1 ALK5 SKR4

Gene ID

7046

Swiss Prot

P36897

Host

Mouse

Reactivity

Human; Mouse; Rat; Bovin

Immunogen

A synthetic peptide corresponding to the amino acid region 34 - 100 of the human TGF β Receptor I protein.

Clonality

Monoclonal

Source

Monoclonal, Mouse, IgG

Applications

IHC

Purification

The antibody was purified by protein G affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can specifically recognize human TGF β Receptor I protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Protein Name

TGF β Receptor I

Available Sizes

Frequently Asked Questions

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