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KSP-Cadherin (AB1515) Mouse mAb (Ready to Use)

Product Specifications

Background

KSP- cadherin, also known as cadherin- 16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP- cadherin has a sensitivity of up to 100% in renal chromophobe cell carcinoma and 95% in renal eosinophilic adenoma.

Synonyms

Cadherin-16 (Kidney-specific cadherin, Ksp-cadherin)

Gene Name

CDH16 UNQ695/PRO1340

Gene ID

1014

Swiss Prot

O75309

Host

Mouse

Reactivity

Human; Mouse

Immunogen

A synthetic peptide corresponding to the amino acid region 1 - 100 of the human KSP - Cadherin protein.

Clonality

Monoclonal

Source

Monoclonal, Mouse, IgG

Applications

Immunohistochemistry (IHC)

Purification

The antibody was purified by protein G affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can specifically recognize human KSP- Cadherin protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Protein Name

KSP-Cadherin

Available Sizes

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