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P57kip2 (AB1822) Rabbit mAb (Ready to Use)

Product Specifications

Background

P57kip2 is a cell cycle inhibitor and tumor suppressor. The gene is mainly located on the mother's chromosome 11. By blocking the G1 / S phase transition in the cell cycle, we can realize the negative regulation of the cell cycle, and then prevent cell proliferation and tumor formation. In complete hydatidiform mole, there is a lack of maternal gene and p57 negative expression, while in partial hydatidiform mole, there are genes of both parents and p57 positive expression, which can be used for the study of early hydatidiform mole pregnancy.

Synonyms

Beckwith Wiedemann syndrome; BWCR; BWS; CDKI; CDKN 1C; CDKN1C; CDN1C_HUMAN; Cyclin dependent kinase inhibitor 1C; Cyclin dependent kinase inhibitor p57; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; KIP 2; KIP2; p57; p57 Kip 2; p57KIP2; WBS

Gene Name

CDKN1C

Gene ID

1028

Swiss Prot

P49918

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 200 - 316 of the human p57kip2 protein.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

IHC

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can specifically recognize human p57kip2 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Protein Name

P57kip2

Available Sizes

Frequently Asked Questions

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