MutS Protein Homolog 6 (MSH6) (AB1819) Rabbit mAb (Ready to Use)
Product Specifications
Background
MSH6 is an important gene in the human mismatch repair gene family, which is located at position 16 of the p arm of chromosome 2. Human mismatch repair genes play an important role in maintaining the integrity and stability of genetic information and avoiding genetic mutation. The deletion of this gene after mutation will make the cell mismatch repair function defective, lead to microsatellite instability (MSI), and make the tumor susceptible. Clinically, it is often used in the screening of Lynch syndrome together with mismatch repair proteins MLH1, MSH2 and PMS2.
Synonyms
DNA mismatch repair protein Msh6; G/T mismatch binding protein; G/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC 5; HNPCC5; HSAP; MSH 6; MSH6; MSH6_HUMAN; mutS (E. coli) homolog 6; MutS alpha 160 kDa subunit; MutS homolog 6 (E. coli) ; mutS homolog 6; MutS-alpha 160 kDa subunit; p160; Sperm associated protein
Gene Name
MSH6
Gene ID
2956
Swiss Prot
P52701
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 900 - 1000 of the human MutS Protein Homolog 6 protein.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
IHC
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
It has been optimized for direct use, requiring no further dilution.
Modification
Unmodified
Storage Conditions
Store at 4°C. Avoid freeze.
Specificity
The antibody can specifically recognize human MSH6 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Protein Name
MutS Protein Homolog 6 (MSH6)
Available Sizes
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