MDR1 (AB1689) Rabbit mAb (Ready to Use)

Product Specifications

Background

MDR- 1, also known as P- 170, is a membrane glycoprotein encoded by MDR gene. Its main function is to quickly pump cytotoxic drugs out of cells by ATP. Its expression level is related to the permeability of cell membrane, intracellular drug concentration and the degree of drug resistance. It is mainly used in the study of tumor drug resistance.

Synonyms

ABC20; ABCB1; ATP binding cassette, sub family B (MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1

Gene Name

ABCB1

Gene ID

5243

Swiss Prot

P08183

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

A synthetic peptide corresponding to the amino acid region 600 - 700 of the human MDR1 protein.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

IHC

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can specifically recognize human MDR1 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Protein Name

MDR1

Available Sizes

Curated Selection

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