Cytokeratin Pan (AB1382) Rabbit mAb (Ready to Use)

Product Specifications

Background

Cytokeratin can label keratinized epithelium, stratified squamous epithelium, stratified epithelium, proliferative keratinized cells and monolayer epithelium. It can be used in the study of various cancers. It is positive in various adenocarcinoma, small cell carcinoma, transitional cell carcinoma, malignant mesothelioma, germ cell tumors other than seminoma, leiomyosarcoma and some synovial sarcomas. CEA and EMA can be combined for the differential diagnosis of epithelial tumors and non epithelial tumors.

Synonyms

Pan cytokeRatin; wide spectrum CytokeRatin; AE1; AE3

Gene Name

KRT10 KRT13 KRT14 KRT15 KRT16 KRT19

Gene ID

3858; 3860; 3866; 3861; 3880; 3868

Swiss Prot

P13645; P13646; P02533; P19012; P08779; P08727

Host

Rabbit

Reactivity

Human; Mouse (predicted: Rat)

Immunogen

A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Cytokeratin protein.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

IHC

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

It has been optimized for direct use, requiring no further dilution.

Modification

Unmodified

Storage Conditions

Store at 4°C. Avoid freeze.

Specificity

The antibody can recognize multiple human Cytokeratins, including CK10, 13, 14, 15, 16, 18, 19, and it can be used for immunohistochemical detection of tumors from monolayer and multilayered epithelium.