CD8 a (AB1293) Rabbit mAb (Ready to Use)
Product Specifications
Background
CD8 is a 68kDa transmembrane glycoprotein consists of two subunits, αβ heterodimer or αα homodimer linked by a disulfide. CD8 is mainly expressed on the surface of suppress/cytotoxic T cells and NK cells. It is detected to be positive in T- cell large granular lymphocytic leukemia and subcutaneous panniculitis like T- cell lymphoma, and can be a marker for Precursor T lymphoblastic leukemia / lymphoma. CD8 is negative in Mycosis Fungoides and non- hematolymphoid neoplasms.
Synonyms
Alpha polypeptide (p32) ; CD_antigen=CD8a; CD8; CD8 antigen alpha polypeptide; CD8 antigen alpha polypeptide (p32) ; CD8 antigen, alpha polypeptide (p32) ; CD8a; CD8A antigen; CD8A molecule; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; Ly 2; Ly 35; Ly B; Ly2; Ly3; Ly35; LyB; Lyt 2. 1 lymphocyte differentiation antigen (AA at 100) ; LYT3; MAL; OKT8 T cell antigen; OTTHUMP00000160760; OTTHUMP00000160764; OTTHUMP00000203528; OTTHUMP00000203721; p32; T cell antigen Leu2; T cell co receptor; T lymphocyte differentiation antigen T8/Leu 2; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein Lyt 2; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen; T8/Leu-2 T-lymphocyte differentiation antigen
Gene Name
CD8A
Gene ID
925
Swiss Prot
P01732
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 235 of the human CD8 a protein.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
IHC
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
It has been optimized for direct use, requiring no further dilution.
Modification
Unmodified
Storage Conditions
Store at 4°C. Avoid freeze.
Specificity
The antibody can specifically recognize human CD8 protein, including two typies of dimer: αβ heterodimer or αα homodimer.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Protein Name
CD8 a
Available Sizes
Curated Selection
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