CD105 (Endoglin) (AB1278) Rabbit mAb (Ready to Use)
Product Specifications
Background
CD105 is a homodimeric cell membrane glycoprotein linked by disulfide bonds. It is a new class of cell adhesion molecules and plays an important role in regulating angiogenesis. As a receptor of TGF- beta, CD105 is highly expressed in vascular endothelial cells of tumor related neovascular endothelium. Therefore, the evaluation of tumor microvessel density by immunohistochemical staining is significantly correlated with tumor invasion and prognosis.
Synonyms
AI528660; AI662476; CD 105; CD105; CD105 antigen; EGLN_HUMAN; END; Endoglin; Eng; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15. 2; S endoglin; S-endoglin; SN6
Gene Name
ENG
Gene ID
2022
Swiss Prot
P17813
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 500 of the human CD105 protein.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
IHC
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
It has been optimized for direct use, requiring no further dilution.
Modification
Unmodified
Storage Conditions
Store at 4°C. Avoid freeze.
Specificity
The antibody can specifically recognize human CD105 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Protein Name
CD105
Available Sizes
Frequently Asked Questions
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