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MSH2 (AB1240) mouse mAb

Product Specifications

Background

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Synonyms

DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, hMSH2

Gene Name

MSH2

Gene ID

3662

Swiss Prot

P43246

Host

Mouse

Reactivity

Human

Immunogen

Recombinant protein of the human MSH2 protein.

Clonality

Monoclonal

Source

Monoclonal, Mouse, IgG

Applications

IHC; WB

Purification

The antibody was purified by protein G affinity chromatography.

Dilution

IHC, 1:100-1:400 | WB, 1:2000-1:10000

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of MSH2 protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

MutS Protein Homolog 2

Available Sizes

Frequently Asked Questions

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