MLH1 (AB1236) mouse mAb
Product Specifications
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009]
Synonyms
DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1
Gene Name
MLH1 COCA2
Gene ID
4292
Swiss Prot
P40692
Host
Mouse
Reactivity
Human
Immunogen
Recombinant protein of the human MLH1 protein.
Clonality
Monoclonal
Source
Monoclonal, Mouse, IgG
Applications
IHC; WB
Purification
The antibody was purified by protein G affinity chromatography.
Dilution
IHC, 1:100-1:400 | WB, 1:2000-1:10000
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of MLH1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
MutL Protein Homolog 1
Available Sizes
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