SRP72 (AB2259) Rabbit mAb
Product Specifications
Background
This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER) . The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Synonyms
SRP72, Signal recognition particle subunit SRP72 , SRP72, Signal recognition particle 72 kDa protein
Gene Name
SRP72
Gene ID
6731
Swiss Prot
O76094
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF/ICC, Flow Cyt
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 | FC, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. |
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of SRP72 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
SRP72
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
