UPB1 (AB2247) Rabbit mAb

Product Specifications

Background

This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]

Synonyms

UPB1, BUP1, Beta-ureidopropionase , BUP-1, Beta-alanine synthase, N-carbamoyl-beta-alanine amidohydrolase

Gene Name

UPB1, BUP1

Gene ID

51733

Swiss Prot

Q9UBR1

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, IHC, IP

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:1000-1:5000 | IHC, 1:·100-1:300 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. |

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of UPB1 protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

UPB1

Available Sizes

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