KLHL6 (AB2244) Rabbit mAb
Product Specifications
Background
This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Synonyms
KLHL6, Kelch-like protein 6
Gene Name
KLHL6
Gene ID
89857
Swiss Prot
Q8WZ60
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IF/ICC, IP
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:1000-1:5000 | IF, 1:100-1:300 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. |
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of KLHL6 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
KLHL6
Available Sizes
Frequently Asked Questions
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