CREB-1 (Phospho Ser133) (AB2303) Rabbit mAb
Product Specifications
Background
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Synonyms
CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1
Gene Name
CREB1
Gene ID
1385
Swiss Prot
P16220
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB; IHC; IF; IP; ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:2000-1:10000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Phospho S133
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
The antibody detects endogenous levels of CREB-1 protein only when phosphorylated at Ser133. The antibody does not cross-react with CREB-1 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
Cyclic AMP-responsive element-binding protein 1
Available Sizes
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