CD89 (AB2217) Rabbit mAb
Product Specifications
Background
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
FCAR, CD89, Immunoglobulin alpha Fc receptor , IgA Fc receptor, CD antigen CD89
Gene Name
FCAR, CD89
Gene ID
2204
Swiss Prot
P24071
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF/ICC, Flow Cyt, IP
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:1000-1:5000 | IHC, 1:·100-1:300 | IF, 1:100-1:300 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | FC, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of CD89 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
CD89
Available Sizes
Frequently Asked Questions
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