CD89 (AB2217) Rabbit mAb

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

WB, 1:1000-1:5000 | IHC, 1:·100-1:300 | IF, 1:100-1:300 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | FC, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.