ULK1 (Phospho Ser757) (AB2194) Rabbit mAb

Product Specifications

Background

Catalytic activity:ATP + a protein = ADP + a phosphoprotein. , function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells. , similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. , similarity:Contains 1 protein kinase domain. , subunit:Interacts with GABARAP and GABARAPL2. , tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.

Synonyms

ULK1, KIAA0722, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, ATG1, hATG1, Unc-51-like kinase 1

Gene Name

ULK1

Gene ID

8408

Swiss Prot

O75385

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, IF, IP, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Phospho S757

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

The antibody detects endogenous levels of ULK1 protein only when phosphorylated at Ser757. The antibody does not cross-react with ULK1 phosphorylated at other sites.