ULK1 (Phospho Ser757) (AB2194) Rabbit mAb
Product Specifications
Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein. , function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells. , similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. , similarity:Contains 1 protein kinase domain. , subunit:Interacts with GABARAP and GABARAPL2. , tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.
Synonyms
ULK1, KIAA0722, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, ATG1, hATG1, Unc-51-like kinase 1
Gene Name
ULK1
Gene ID
8408
Swiss Prot
O75385
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Phospho S757
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
The antibody detects endogenous levels of ULK1 protein only when phosphorylated at Ser757. The antibody does not cross-react with ULK1 phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
ULK1 (Phospho Ser757)
Available Sizes
Frequently Asked Questions
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