CGAS (AB2161) Rabbit mAb
Product Specifications
Background
Enables several functions, including 2', 3'-cyclic GMP-AMP synthase activity, molecular condensate scaffold activity, and phosphatidylinositol-4, 5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont, intracellular signal transduction, and regulation of defense response. Located in nuclear body, plasma membrane, and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Protein MB21D1 (Mab-21 domain-containing protein 1)
Gene Name
MB21D1 cGAS C6orf150
Gene ID
115004
Swiss Prot
Q8N884
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of cGAS protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
CGAS
Available Sizes
Frequently Asked Questions
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