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Fascin (AB1621) Rabbit mAb

Product Specifications

Background

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Synonyms

Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Gene Name

FSCN1 FAN1 HSN SNL

Gene ID

6624

Swiss Prot

Q16658

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB; IHC; IF; IP; ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:10000-1:20000 | IHC, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Available Sizes

Frequently Asked Questions

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