C-Jun (AB1980) Rabbit mAb
Product Specifications
Background
Function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. , PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. , similarity:Belongs to the bZIP family. , similarity:Belongs to the bZIP family. Jun subfamily. , similarity:Contains 1 bZIP domain. , subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity) . Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5, indirectly leading to its phosphorylation. Interacts with DSIPI, this interaction inhibits the binding of active AP1 to its target DNA.
Synonyms
Transcription factor AP-1 (Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39)
Gene Name
JUN
Gene ID
3725
Swiss Prot
P05412
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of c-Jun protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
C-Jun
Available Sizes
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