Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Bax (AB1837) Rabbit mAb

Product Specifications

Background

The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero-or homodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.

Synonyms

BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4

Gene Name

BAX

Gene ID

581

Swiss Prot

Q07812

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, IHC, IF, IP, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:1000-1:5000 | IHC, 1:2000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of Bax protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

Bax

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PEnCMV-Ash1l (mouse) (1-2135aa) (2136-2958aa) -Myc-FLAG-SV40-Neo
BZ43406 1 Vial

PEnCMV-Ash1l (mouse) (1-2135aa) (2136-2958aa) -Myc-FLAG-SV40-Neo

Sign In for Pricing
View Details
hsa-miR-4659b-5p Primers
MPH02830 150 µL / 10 µM

hsa-miR-4659b-5p Primers

Sign In for Pricing
View Details
Tasp1 ORF Vector (Mouse) (pORF)
46212015 1.0 µg DNA

Tasp1 ORF Vector (Mouse) (pORF)

Sign In for Pricing
View Details
LRRC37A8P Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV767071 1.0 µg DNA

LRRC37A8P Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

Sign In for Pricing
View Details
CD27 Rabbit mAb
A24889 100 µL

CD27 Rabbit mAb

Sign In for Pricing
View Details
Goat PAF-AH ELISA Kit
EGTP0580 96 Tests

Goat PAF-AH ELISA Kit

Sign In for Pricing
View Details